Medcara, LLC.

WartPEEL vs. Other 5FU/SA Compounds

WartPEEL’s proprietary patented Remedium Adhesive Gel was designed specifically to treat warts.  The traditional vehicle like creams, ointments solutions and pastes are better suited for rashes because they spread and dilute. This is not what you want in a topical wart formula. Tape is often used in an effort to control the spread but this doesn’t work.

To illustrate the difference, we added a blue dye to WartPEEL adhesive gel and a compounded 5-FU and salicylic acid, the same active ingredients as WartPEEL in a paste from another compounding pharmacy. Tape was applied after WartPEEL was fully dried. Tape was also applied to the paste after application according to the manufacturer's instructions.

You can see that after the WartPEEL Dries it actually turns a darker blue. This is due to evaporation and concentration. The next morning, WartPEEL stayed in exactly the same place as it was after it dried.

Meanwhile the paste had spread under the tape. This dilutes it’s strength which is evident by its lighter blue color. Perilesional irritation and inflammation is commonly reported from wart medications in traditional vehicles due to this spread to the perilesional skin. This leads to a long intermittent treatment that lasts months.

The results of the dye test for the anhydrous paste used as the comparator for WartPEEL could be generalized to include any anhydrous formula, which is the vast majority of our competitors (unless they're doing a 35d BUD or doing a stab indicating study).  As long as the competitor formula lacks a volatile/evaporative component, then it's going to smear similar to the paste when they occlude it.


 

WartPeel 

Competing Generic Compounded Paste

 

 

WartPEEL Immediately After Application
WartPEEL Immediately After Application
WartPEEL After it Has Dried Note: It has concentrated and the color is darker blue.
WartPEEL After it Has Dried Note: It has concentrated and the color is darker blue.
WartPEEL the Next Morning After Tape is Removed. WartPEEL Has Not Spread.
WartPEEL the Next Morning After Tape is Removed. WartPEEL Has Not Spread.

5-FU/Sal Acid Paste Immediately After Application
5-FU/Sal Acid Paste Immediately After Application
15 Minutes Following Application of the Paste
15 Minutes Following Application of the Paste
5-FU/Sal Acid Paste the Next Morning After Tape is Removed
5-FU/Sal Acid Paste the Next Morning After Tape is Removed

 

 


 

WartPEEL

WartPEEL Immediately After Application - blue dye on finger

WartPEEL Immediately After Application

WartPEEL After it Has Dried - darker blue on finger

WartPEEL After it Has Dried

Note: It has concentrated and the color is darker blue.

WartPEEL the Next Morning After Tape is Removed

WartPEEL the Next Morning After Tape is Removed. WartPEEL Has Not Spread

 

 

Competing Generic Compounded Paste

5-FU/Sal Acid Paste Immediately After Application

5-FU/Sal Acid Paste Immediately After Application

15 Minutes Following Application of the Paste

15 Minutes Following Application of the Paste

5-FU/Sal Acid Paste the Next Morning After Tape is Removed

5-FU/Sal Acid Paste the Next Morning After Tape is Removed

 

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